Mykola I. Lisianiy +380 44 483-81-93
The neuroimmunology department was set up in 1985 as part of an immunology laboratory of the Institute of Neurosurgery. The department is a leading scientific subunit in the field of neuroimmunology of Ukraine, a center that develops and implements modern immunological and genetic methods of laboratory diagnosis in patients with CNS pathology. The department has developed and introduced immunoferment methods to assess formations of antibodies to cerebral tissue proteins, as well as classical immunological methods to assess the immune status and immune humoral response. Methods of molecular-biological research, analysis of gene expression in peripheral blood cells and CNS tumors are actively introduced. The department staff take part in international scientific forums and establish contacts with counterparts from other institutions.
Head of the department – honored science and technology worker of Ukraine, corresponding member of the National Academy of Medical Science of Ukraine, PhD, Professor Mykola Ivanovych Lisianiy.
О.V.Markova and I.O.Hnedkova, candates of medical science, and L.D.Liubych and L.M.Belska, candidates of biological sciences, as well as A.I.Kliuchkova, a research assistant, work in the department.
Professor Lisianiy Mykola Ivanovych – an honored science and technology worker of Ukraine, corresponding member of the National Academy of Medical Science of Ukraine, PhD head of the neuroimmunology department. Key areas of research and practice include neuroimmunology, neurogenetic immunodeficiency, immunopathological mechanisms of development of neuropathies, neuroimmune mechanisms of radiation-induced encephalopathy development under the effect of small doses of irradiation. Under his guidance 3 doctoral and 19 candidate dissertations were completed. Author of 400 scientific works, 9 monographs.
Senior researcher Markova Olha Volodymyrivna –candidate of medical science. Key areas of research and practical activity include the immune status of a healthy human being; anti-tumour immunity; pathophysiology inflammatory-degenerative damage of CNS and mechanisms of therapeutic effect of neurotransplantation; development of methods to use hemopoietic stem cells in neurology and neurosurgery. Author of 109 scientific works, including 19 publications abroad, 6 patents of Ukraine, 3 technical innovations, co-author of 4 monographs.
Senior researcher Gnedkova Iryna Oleksandrivna – candidate of medical science, immunologist of the highest qualification category in the specialty “clinical immunology”. Key areas pf research and practical activity include study of clinical significance of changes in the immune system in patients with CNS diseases (brain tumors, injury, neuro-infeciton, epilepsy, multiple encephalomyelitis, etc.), development of methods and approaches to immune correction of CNS diseases; study of anti-tumor immunity mechanisms; study of immunological properties of neural stem cells. Author of 76 scientific works, including 16 publications abroad, 2 Patents of Ukraine, 3 technical innovations, co-author of 4 monographs.
Senior researcher Liubych Larysa Dmytrievna -candidate of biological sciences. Key areas of research and practical activity – study of immunomodulating and anti-tumour properties of cells of embryonic and fetal brain, study of proapoptogenic and local immuno-suppression activity of CNS tumors, study of autoimmune reaction to brain antigens in patients with normal conditions and CNS pathologies. Author of 119 scientific works, including 32 publications abroad, 3 Patents of Ukraine, co-author of 5 monographs.
Senior researcher Belska Liudmyla Mykolaivna – candidate of biological sciences. Key areas of research and practical activity include study of systemic and local (in CNS tissue) changes in the state of phagocytes in patients with normal conditions, during neurotransplantation and with pathological conditions (gliomas, experimental allergic encephalomyelitis). Author of 74 scientific works, including 12 publications abroad, co-author of 2 monographs.
Research assistant Kliuchkova Antonina Ivanivna – key areas of research and practical activity include study of the dynamics of development of immune responses to intracerebral and intramuscular injection of alloantigens (experimental study). Author of 12 scientific works.
11. Lisianiy M.I., Belska L.M., Lisianiy O.M, Fedorchyk O.H. The effect of in vitro amitosin and ВС-1 on CNS tumors of various genesis and immuno-competent cells // Immunology and allergology.-2007,#1.-p.42-46.
1. Immune status:
1) homogenous antibodies panel (13 types)
2. Neuroimmune responses: level of antibodies vs. neuroantigens (ОБМ, S-100, acid glial proteid, neurospecific enolase), neuro sensibilization to the above-mentioned antigens.
3. Determination of levels of pro- and anti-inflammatory cytokines in blood, in supernatants (інтерлейкін-1; 4; 6; 8; 10; interferon-α, γ, ФНО- α , etc.).
4. ELISA for various viruses, immune antigens in blood and bodily fluids.
5. Polymerase chain reaction (DNA and RNA tests) to detect 20 types of agents causing neuroinfections, gnetic and malignant blood diseases.
1. Immunodeficiency and autoimmune diseases, including CNS diseases.
2. Neurooncological and neurovascular diseases (gliomas, medulloblastomas, ischemic and hemorrhagic lesions).
3. Epilepsies, hyperkinetic disorder, children cerebral palsy.
4. Multiple sclerosis, encephalopathy, polyneuropathy of different etiology;
5. Chronic fatigue syndrome, febrile states.
The Neuroimmunolofy department staff provide counseling assistance. If you have any questions, you can emal to firstname.lastname@example.org
Our address: 04050, Kyiv, 32 Platona Mayborody St., Institute of Neurosurgery, Neuroimmunology department (laboratory block, 5th floor). How to find us – take trolleybus #6, 18 from the “Lukyanivska” metro station to the stop “Bohoutivska Street”, then walk to Platona Mayborody street.
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